The US has killed the leader of al-Qaeda, Ayman al-Zawahiri, in a drone strike in Afghanistan
He was killed in a counter-terrorism operation carried out by the CIA in the Afghan capital of Kabul on Sunday.
Mr Biden said Zawahiri had "carved a trail of murder and violence against American citizens".
Zawahiri, who just turned 71 years old, had remained a visible international symbol of Osama Bin Laden's group
At one point, he acted as bin Laden's personal physician.
Zawahiri took over al-Qaeda after the death of Bin Laden in 2011.
Other family members were present, but they were unharmed and only Zawahiri was killed in the attack, officials told.